Genomics of Euglena
The genome of Euglena is highly complex for a simple free living cell. The total amount of DNA is similar to that of Human cells and there are more genes encoded. It is not clear why Euglena needs all these genes. The aim of this project is to sequence related Euglena, at transcriptomic, genomic and metagenomic levels. Euglena controls gene expression at post transcriptionally, meaning that the transcriptome at any given time is a good representation of the genome, and avoids the difficulties of sequencing their large complex genome. Comparing the gene between different species will help us to understand the capacity of these cells.
Work published on sequencing of Euglenozoa
The transcriptome of Euglena gracilis reveals unexpected metabolic capabilities for carbohydrate and natural product biochemistry
The first transcriptome of Euglena gracilis that we published, showing its huge genetic capacity
Download a translation of the Euglena transcriptome from this publication
The new transcriptome, with the first draft genome of Euglena gracilis.
Euglena in time: Evolution, control of central metabolic processes and multi-domain proteins in carbohydrate and natural product biochemistry
A deeper look into the trancriptome of Euglena gracilis